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Diurnal versus office

2024-07-16 07:58| 来源: 网络整理| 查看: 265

J Optom. 2015 Oct-Dec; 8(4): 239–243. Published online 2014 Jun 16. doi: 10.1016/j.optom.2014.05.005PMCID: PMC4591418PMID: 26386536

Language: English | Spanish

Diurnal versus office-hour intraocular pressure fluctuation in primary adult onset glaucomaComparación de la fluctuación de la presión intraocular diurna y en horario de consulta en pacientes con glaucoma primario de aparición en la edad adultaTarun Arora,a Shveta Jindal Bali,b Vishal Arora,a Meenakshi Wadhwani,a Anita Panda,a and Tanuj Dadaa,⁎Tarun Arora

aDr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India

Find articles by Tarun AroraShveta Jindal Bali

bIvey Eye Institute, Schulich School of Medicine and Dentistry, London, ON, Canada

Find articles by Shveta Jindal BaliVishal Arora

aDr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India

Find articles by Vishal AroraMeenakshi Wadhwani

aDr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India

Find articles by Meenakshi WadhwaniAnita Panda

aDr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India

Find articles by Anita PandaTanuj Dada

aDr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India

Find articles by Tanuj DadaAuthor information Article notes Copyright and License information PMC DisclaimeraDr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, IndiabIvey Eye Institute, Schulich School of Medicine and Dentistry, London, ON, CanadaTanuj Dada: moc.liamg@adadjunat ⁎Corresponding author at: Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India. moc.liamg@adadjunatReceived 2014 Feb 1; Accepted 2014 Apr 6.Copyright © 2014 Spanish General Council of Optometry. Published by Elsevier España, S.L. All rights reserved.AbstractPurpose

To evaluates the role of measuring intraocular pressure (IOP) outside office-hour in primary adult onset glaucoma.

Methods

This retrospective study included 100 cases of primary adult onset glaucoma. IOP readings obtained with Goldmann applanation tonometry between 7 am and 10 pm were compared to office-hour readings.

Results

One hundred patients were enrolled (mean age: 58.64 ± 10.98 years) in the study. Overall, mean diurnal IOP was significantly higher than mean office IOP (p Table 1

Intraocular pressure (IOP) characteristics across the study population.

Mean diurnal IOP (IOPd)Mean office IOP (IOPo)p value (IOPd vs. IOPo)Diurnal IOP fluctuation (IOPdf)Office IOP fluctuation (IOPof)p value(IOPd vs. IOPo)All subjects (n = 100)16.11 ± 3.1413.19 ± 4.250.027.03 ± 2.694.31 ± 2.60.03PACG (n = 50)16.14 ± 2.7513.13 ± 4.440.027.04 ± 2.364.00 ± 2.630.02POAG (n = 50)16.02 ± 3.5013.32 ± 4.070.017.38 ± 3.115.06 ± 2.620.01Open in a separate window

IOP: Intraocular pressure; POAG: Primary open angle glaucoma; PACG: Primary angle closure glaucoma.

Peak IOP was reached most often at 7 am (42/100; 42%) followed by 10 pm (23/100; 23%). The percentage of patients having their IOP peak at 10 am, 1 pm, 4 pm, and 7 pm were 20.9%, 3.4%, 6.1%, and 4.3% respectively. Thus, two-third of the patients had their IOP peak outside the office hours (Fig. 1).

Open in a separate windowFigure 1

Frequency of peak IOP measurements (y axis) across various times of the day (x axis).

On comparing the PACG and the POAG subjects, there was no significant difference between the two groups with respect to mean diurnal IOP (p = 0.31), mean office IOP (p = 0.24), mean diurnal fluctuation (p = 0.45) and mean office fluctuation (p = 0.63).

The overall mean baseline IOP (pretreatment) was 24.20 ± 4.61 mm Hg (PACG: 25.00 ± 4.69 mm Hg; POAG: 23.40 ± 4.41 mm Hg, p = 0.46). The patients were grouped into those with diurnal fluctuation greater or less than 4 mm Hg. The mean baseline IOP was 25.01± 4.21 mm Hg in the former group and was 20.17 ± 2.32 mm Hg in the latter (p = 0.001). Statistically significant correlation was noted between the baseline IOP and IOP fluctuation (r = 0.61, p 



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